150-180 . A careful read of this systematic review and meta-analysis will yield the following statements by the research team: Whether menaquinone-4 is more effective as an anti-osteoporotic agent than phytonadione (Vitamin K1) remains to be established, but both forms can be used for carboxylation (of osteocalcin). Low vitamin K intake has also been linked to increased risk of hip fractures in men and women and to low bone density in women. Vitamin K has long been known to be important for blood clotting. Promotes bone marrow stem cell proliferation. How much K2 do I need with D3? New Insights into the Biology of Osteocalcin. Some have found improved bone mineral density, a few showed decreased fracture risk, and others found no additional benefit to bone health. This is likely an indication of the importance of production from bacteria fermentation as compared to production by the grass-fed animal. Vitamin K2 vs. Vitamin K1 Uses Foods Dosage Deficiency Symptoms Risks and Side Effects Full-fat cheeses, eggs and beef liver might not be the types of foods that come to mind when you think about eating a heart-healthy diet. . Our findings should be treated cautiously, however, because the studies were not primarily designed to show a fracture effect. These findings cannot be explained by our current understanding of the biochemical role of vitamin K, but suggest that vitamin D may influence vitamin K-dependent proteins.. In fact, talking about it is making me hungry wheres my saucepan! Instant breakfast drink, various flavors and brands, powder prepared with water, 8 ounces 105-250 mg per serving. Calcium: Recommended daily amount; Men ; 19-50 years: 1,000 mg: 51-70 years: 1,000 mg: 71 and older: 1,200 mg: Women ; 19-50 years: 1,000 mg: 51 and . Thank you. Many Americans don't get enough calcium in their diets. In reply to scolioporosis's comment. Cleveland Clinic is a non-profit academic medical center. Hi Denise: You should discuss this question with your physician who prescribes the Zoloft. I am sure if you devote enough time on the internet to any topic, youll find radically different, strongly formulated, and firmly held opinions. Megan. You should consult with a registered/licensed nutritionist. I am taking MK4 (took MK7 before that) and have tried to have my K levels checked. MK-7 and Its Effects on Bone Quality and Strength - PMC Vitamin K1 is processed in the liver and plays a larger role in the coagulation of our blood, whereas Vitamin K2, on the other hand, is processed in the intestine. But osteocalcin needs Vitamin K2 to function optimally.. Read more about bone-healthy nutrients at americanbonehealth.org. Oh, dear. Incidentally, Ive increased my bone density in my lumbar spine between age 47 an 53. Below is a video from several years ago where I discuss Vitamin K2 and bone health. Before I answer any questions, let me first state that we prepared the article for our patients because many of them are confused by the mixed messages that they read on Vitamin K1 and K2. Bovine liver is one of the few foods with representation of most of the Vitamin K2 sub-groups. But what exercises should you do and which ones should you avoid? ISBN-10: 0-309-07279-4ISBN-10: 0-309-07290-5. This content does not have an English version. The dosage recommendations for MK4 and MK7 differ considerably. Before I identify the foods high in Vitamin K2, we need to spend a bit of time on the two most popular forms of Vitamin K2, namely MK-4 and MK-7 and explore their food sources. Lets tackle what could cause Vitamin K2 deficiency. A great resource on exercise and osteoporosis is my free, seven day email course called Exercise Recommendations for Osteoporosis. My bleeding time was all over the place and I would have to adjust the dosage of coumadin almost every time I was tested. I find that the best way to enjoy eating it is by adding 1/2 teaspoons of strong mustard and some soya sauce. It was not helpful. Key components of an osteoporosis exercise program. A common question is whether you should use MK4 or MK7 for bone health and to treat osteoporosis. . ConsumerLab, an independent testing organization, tested eight K2 supplements for purity, accuracy in labelled amount and absorbency. Oral Diseases. If you're taking a daily multivitamin, it should contain some vitamin K2, typically 10 to 25 mcg, which should be adequate in combination with dietary sources if your bone density is normal. The European Food Safety Authority approved the health claim for Vitamin K but has not offered a dosage recommendation. Her expertise is in the treatment and prevention of osteoporosis through exercise, safe movement and fall prevention. Is it possible that you meant mcg instead of mg? Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Furthermore, treatment with vitamins D and K with calcium increased BMD in older female patients with Alzheimers disease., The authors conclude by stating that animal and human studies suggest that optimal concentrations of both vitamin D and vitamin K are beneficial for bone and cardiovascular health as supported by genetic, molecular, cellular, and some human studies., But they share words of caution, particularly as they relate to overuse of Vitamin D: However, vitamin D and calcium supplementation along with vitamin K deficiency might also induce long-term soft tissue calcification and CVD, particularly in vitamin K antagonist users and other high-risk populations. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials. A study in 2013 found taking 180 mcg daily helped reduce bone loss in healthy women who had been through menopause. Quick Answer: How Much Vitamin K2 Mk7 For Skin Health Per Day In the end, I think you need to decide for yourself. You suggested 45 mg daily. The acid the stomach makes while eating helps the body absorb calcium carbonate. Why this doctor is recommending a dosage that's so much higher than what's in InnovixLabs Vitamin K2 supplement? Several research studies dispute the efficacy of Vitamin K2 in improving bone health. In one study (9) of Vitamin K and bone health the authors concluded there were no differences in changes in bone mineral density measurements at any of the anatomical sites measured between the two groups (the control and study groups)., The other study (9) found no effect of phylloquinone or MK4 on lumbar spine or proximal femur BMD or proximal femur geometric parameters was observed. The authors stated that this study does not support a role for vitamin K supplementation in osteoporosis prevention among healthy, postmenopausal, North American women receiving calcium and vitamin D supplementation.. Thank you so much for taking the time and energy to reply so thoroughly. I searched for a validated research report that compared MK4 to MK7 to see which was the better candidate for the prevention and treatment of osteoporosis but was not successful. Margaret operates her Physical Therapy clinic, MelioGuide Physical Therapy, in Ottawa, Ontario where she focuses on patients with osteoporosis, osteopenia and low bone density. Osteoporosis - Diagnosis and treatment - Mayo Clinic I would need to take a lot of those supplements. Feb 7, 2012 4:42 PM. Effect of vitamin K supplementation on bone loss in elderly men and women. MelioGuide Physical Therapy for Osteoporosis, Physical Therapy Osteoporosis Prevention and Treatment, March 15, 2022 By Margaret Martin 53 Comments. Vitamin K2 Dosage for Osteoporosis Treatment, This article was last updated on August 16, 2022, International Science and Health Foundation, Exercise Recommendations for Osteoporosis, https://melioguide.com/osteoporosis-nutrition/probiotics-bone-loss/. Zoch, ML., et al. I take 45 mcg of K2 (MK7) for osteoporosis. Both Vitamin K1 and K2 support blood clotting and might counteract the effects of ananticoagulants. Hi Margaret thanks for this. If I find anything interesting I will certainly pass it on to you. Multiple Vitamin K Forms Exist in Dairy Foods. I take 45 mcg of K2 (MK7) for osteoporosis. Some experts recommend getting about 150 to 400.Dosage for Osteoporosis. Cholestyramine (Prevalite). A 100 gram serving of egg yolk from grass-fed chickens has MK4 in the following quantity: As I mentioned earlier in this blog post, MK-7 is derived from fermentation but not all fermentation is the same! ( Long answer below) She is the creator of the continuing education course, Working with Osteoporosis and Osteopenia. Here are two articles to get you started: Revised: 10/29/19. The safe upper limit for vitamin D is 100g (4,000 IU) a day. MK4 and MK7 are menaquinones (Vitamin K2) and both appear to be beneficial to bone health. I am on a blood thinner, Coumadin, and got the OK from my cardiologist and the clinic monitored my INR test closely for a few weeks until my K2 dose and INR tests were steady by adjusting my Coumadin dose. Smaller doses most often means 500 milligrams or less at a time. Some, but not all research, demonstrates that people with osteoporosis can use Vitamin K2 to improve both bone density and bone strength. out of DrWeil.com subscriptions at any time. How much K2 should I take with D3? Like curd cheese, Edam cheese is another food with representation of most of the Vitamin K2 sub-groups; although the quantities are low in many of the sub-groups with the exception of MK-8 and MK-9. Core strength and osteoporosis why is core strength important if you have osteoporosis? for all people, who take up to 2500 IU vitamin D per day. [] 2 10-45 . Only MK4 has demonstrated the ability to decrease fractures, the most relevant end point in randomized, controlled clinical trials. We also wrote an article on calcium supplements you might find interesting: https://melioguide.com/osteoporosis-nutrition/calcium-supplements-for-osteoporosis/. I discuss these later in this article. Food Chem. I speak to friends/colleagues at length about the promises of K2 and no, it is not the same of K1!! (. The meta-analysis found that high levels of Vitamin K2 were associated with reduced: As mentioned before, it has been shown that Vitamin K2 is also beneficial for your cardiovascular system. 2018 May 1;23(5). It also showed an improvement in bone strength in the femoral neck and a decreased loss of height in the lower thoracic vertebra. The combination might increase the risk of too much calcium in the blood (hypercalcemia). 2009 Jun;24(6):983-91. doi: 10.1359/jbmr.081254. According to the authors: Human evidence for the role of 1,25(OH)D in stimulating vitamin K-dependent proteins is scarce. A Japanese fermented dish called Nattis particularly abundant in Vitamin K2. Osteocalcin is among the most abundant proteins in bone and is produced exclusively by osteoblasts. Since Dr. Booths report, a new piece of research published in the June 2017 edition ofCurrent Developments in Nutrition, indicate that the amount of vitamin K contents in dairy products is high and proportional to the fat content of the product. (7), Registered Dietitian Nutritionist, Nancy Robinson, points out in her blog article that the research found that low and full fat dairy products contain more Vitamin K2 than previously reported. She also recommends that Vitamin K is a fat soluble vitamin so fat free dairy is not a good source.. Several scientific studies confirm that Vitamin K2 is an effective way to treat osteoporosis and should be part of your health regimen, however, the results are not conclusive. Keep well, Margaret, As a renal dietitian and someone invested in bone health, Im thrilled to read your article on Vitamin K2. This site uses Akismet to reduce spam. After reading the book Vitamin K2 and the Calcium Paradox, I started making Natt at home. Vitamin K2 and Calcium (CAC) Score | Mayo Clinic Connect One more thing, a common misconception among doctors even now is that vitamins K1/K2 promote clotting solely. Another good read available on Amazon is Vitamin K2 and the Calcium Paradox by Canadian Naturopathic Doctor Kate Rheaume-Bleue. DOI: 10.1016/j.maturitas.2020.05.020 Abstract Supplementation with calcium (Ca) and/or vitamin D (vitD) is key to the management of osteoporosis. Vitamin K2 Vital for Health and Wellbeing. Osteoporos Int. 316 15 691 What Is Vitamin K2? Just wanting to know if cheddar, swiss, etc. If you do not find anything in your smaller city there is a good online supplement shop that I like out of Victoria: http://www.canadianvitaminshop.com If youre like me and get frustrated searching through their web site, call them. Does Vitamin K2 make your hair grow? Several research projects indicate that Vitamin K2, in particular, can play a role in reducing the risk of several cancers, including prostate and liver cancers. Analysis of Menaquinone-7 Content and Impurities in Oil and Non-Oil Dietary Supplements. Stop the stoop how to avoid kyphosis and rounded shoulders. I have noticed that people who advocate fermented foods align with the MK7 solution. This content does not have an Arabic version. This optimal dose (45 mg/day) for the treatment of osteoporosis is about 150-180 times greater than the recommended daily dietary intake of vitamin K (250-300 g) [8]. Second, we have no financial interest in the supplement, K1, K2 or vitamin business. Thank you, Emma. Another important point is discussed below. Thank you for your in-depth research! Consequently, the skeleton becomes more resistant and less susceptible to fracture. MK4 and MK7 are menaquinones (Vitamin K2) and both appear to be beneficial to bone health. Vitamin D and Vitamin K2 and Calcium Balance - Dr. Alex Rinehart I anticipate more research in this area with the result that more questions will be answered about menaquinones and bone health. fauxpilgrim says. As I said, I consume 800 mg of magnesium glycinate. In parts of Asia and specifically, Japan, the daily recommended dosage of MK-4 is 45 mg. The dosage for Vitamin K2 MK-7 is 180 g/day. If you prefer to get your Vitamin K2 from animal-based sources, then you will need to consume their product. Hi Karen. Vitamin K2 keeps the calcium out of the heart and arteries, you should be consuming 600 mg of calcium. All I can share with you is our experience with ConsumerLab. Is there something about the Gouda and Edam process that is different. Hj Margaret, I am 37 and I have osteoporosis of the spine/osteopenia of the hip due to not absorbing calcium/vitamin D properly for many years before I was diagnosed with ulcerative colitis. In this blog post, I discuss Vitamin K2 and osteoporosis. Unless you are actively increasing your Vitamin K2 levels through diet or supplementation, you are likely deficient and have inadequate levels for your bone and heart health needs. All books are available on Amazon in both print and Kindle formats. MK-4 dosages were at either 15 mg/day (1 trial) or 45 mg/day (6 trials). If youre taking a daily multivitamin, it should contain some vitamin K2, typically 10 to 25 mcg, which should be adequate in combination with dietary sources if your bone density is normal. Furthermore, long-term use of these anti-coagulant medicines is associated with accelerated bone loss and low bone mass. Collagen production, and thus, bone quality may be affected by MK-7 or MK-4 converted from MK-7. Margaret has presented at the Canadian Physiotherapy Association and the Ontario Physiotherapy Association on treating aging adults and osteoporosis. (10). Several causes of Vitamin K2 deficiency (11) are: Individuals with malabsorption issues my have inadequate levels of Vitamin K. These syndromes include: Studies found that when people take lots of calcium, the calcium coated their arteries and caused potential heart problems. In his book, Vitamin K2:The Missing Nutrient for Heart and Bone Health, Dr. Dennis Goodman, a cardiologist in New York City, also recommends between 150 to 180 g/day of MK-7 Vitamin K2 (16). Some foods as simply far better than others when it comes to MK-7 and a number of fermented foods cannot be counted on to provide adequate levels of MK-7. https://melioguide.com/osteoporosis-nutrition/probiotics-bone-loss/, Can you take bit k2 with Methatrexate and Zoloft and crestor. Arch Intern Med 2006;166:125661. Regarding bone health: the Nurses Health Study that followed more than 72,000 women for 10 years found that those whose vitamin K intakes were lowest had a 30 percent higher risk of hip fracture than those with the highest vitamin K intakes (at least 110 mcg). The article points out that the Dutch study successfully used K2/MK7 supplements and the ConsumerLab report identifies two standalone MK7 supplements that pass their grade. We receive no compensation from them if you purchase a subscription. Not sure where you draw your vegan line as to what is consumable or not but those are the natural sources you get to choose from. Other supplements like vitamin K2 (VitK2) and magnesium (Mg) could contribute to the maintenance of skeletal health. Margaret, thank you for all the great information. Vitamin K2: Everything You Need to Know - Healthline 2012; 56: 10.3402/fnr.v56i0.5505. The know of only one person who consumes Natt on a regular basis. Vitamin K2 sources include egg yolks, organ meats and natto (a type of fermented soybean). Osteoporosis Int. I was recently diagnosed with severe OP and am finding your videos and blogs super helpful. Some people preferred animal-based products; others fancy fermentation. You are much appreciated!! 1 Reaction REPLY Kanaaz Pereira, Connect Moderator | @kanaazpereira | Apr 9, 2019 Hello @oubobcat, Welcome to Connect. Thank you for your continuing guidance for us with osteoporosis. Vitamin K comes in two forms: Vitamin K1 (phylloquinone) and Vitamin K2 (menaquinone). We are happy with what we see in ConsumerLab. Third, we decided to rely exclusively on published and vetted research as our information source and not other peoples (including supplement manufacturers) interpretations of information. One delicious way to eat it is blitzed in a soup using onion helps to mitigate the smell and removes much of the stickiness. What do you think of taking 45 mg of vitamin K2 daily to keep bones strong? Inhibits osteoclast formation by inhibiting expression of RANKL, and promotes osteoclast apoptosis. Vitamin K2 comes in part from the conversion of K1 in the gastrointestinal tract by gut flora as well as from dietary sources, including some types of meat, egg yolks, fermented dairy products (yogurt and some natural, ripened cheeses) and fermented soy foods, like miso and natto. How much K2 can you take a day? - ElegantQuestion.com This was a much larger effect than foods high in vitamin K1 ( 10 ). We found Dr. Cooperman very knowledgeable, professional and a pleasure to deal with. The topic of Vitamin K can be a little confusing and hard to understand. I was required to get periodic bleeding time tests to get my bleeding time in sync with my diet. I take the various Ks (and have severe osteoporosis) and would love to really know what is worthwhile/best, but its difficult to get accurate information and I was a bit discouraged reading some things on-line about consumerlab. Both seem beneficial to bone health but it is not clear, from the available research, if one is better than the other. That's why it's important we make an extra effort to consume vitamin K2, whether it be via diet or supplementation. What is the relationship between Vitamin D3 with K2, and does the combination of Vitamin D3 and K2 improve bone health? This is based on the dosage used in most recent research studies. The authors review a groups of studies that looked at the effects of Vitamin D3 and Vitamin K2 and go on to state: These findings indicate that combined administration of vitamin D and vitamin K appears to be useful in increasing BMD in postmenopausal women. Please note the date of the last review on all articles. To take 1,000 mg of calcium a day, split it into two or more doses over the day. K2-7 can be taken once daily to maintain K2 levels, whereas K2-4 is taken a few times per day. Also, re ConsumerLab, an independent testing organization and their vit K reports, just a suggestion that people also research them before paying for access to their information. Knapen M.H.J, et al. Based on the connection between vitamin K and bone health, several studies looked at whether it makes sense for anyone, including people with osteoporosis or at risk for it, to take vitamin K supplements. Thank you! Margaret Martin is a Physical Therapist with 36 years of clinical experience. By the way, Ive been following your beginnign osteoporosis exercise program using your book and website resources (thank-you!). Neurodegenerative Disease Prevention. Not consuming adequate levels of either food from grass-fed animals or specific fermented foods. Recommended daily dosage for Vitamin K2 MK4 is 45 mg. You should look for a supplement that identifies the two quantities. Consider supplementing the Natt with a Vitamin K2 efficient cheese like gouda or cheese curds. Soft Cheese:39.5 g/100g ofmenaquinone-9 (MK-9). doi: 10.3390/molecules23051056. Both are common supplements that I will cover, in some detail, in the section dedicated to Vitamin K2. Only two of the group ever get meaningful attention and these are the MK-4 and the MK-7. I credit barbells and vitamin k2 with D3 for these changes. Natt: 998g/100g ofmenaquinone-7 (MK-7). Lets start with your first question regarding whether you should use MK4 or MK7 for bone health and to treat osteoporosis. Binkley N, et al. The findings showed that Vitamin K2 intake significantly decreased age-related decline of both BMC and BMD in areas with the most trabecular bone: the spine and the femoral neck. Vitamin K and Osteoporosis - PMC - National Center for Biotechnology Huang ZB et al. This chart shows how Vitamin K2 directs bone metabolism. Natural Vitamin K2-7 is very important for healthy life e.g. Print ISBN: 978-953-51-3019-2. Several studies support the role of Vitamin K2 in improving bone health. Which form of vitamin K2 is best? - Heimduo What is Vitamin K2 mk7 good for? Second, I do not sell, promote, or have a financial interest in supplement products whether they be Vitamin K1, K2 or other dietary supplements. Recommended daily dosage forVitamin K2 MK4 is45 mg in Asia and Japan. Natto is a much more efficient food source compared to hard or soft cheese. 2015 Apr 1;172:155-60. doi: 10.1016/j.foodchem.2014.09.021. Vitamin K2: What It Is and Its Benefits - Cleveland Clinic Should we be looking for K2 on its own? How Much Vitamin K for Strong Bones? - Ask Dr. Weil Hi Margaret: Ive been taking a supplement by Life Extension its called Bone Restore you take 4 caps divided up to twice a day I found like you said that Calcium without K2 doesnt build bone mass You can find them on line at Life Extension .com with all the amounts of the formula in there so far Im good do not take blood thinners Im not sure how youll feel about the product. If you do take a supplement remember that your body can only absorb a maximum of 500 mg in one sitting. []. Vitamin K1, or phylloquinone, is a compound present in all plants that are photosynthetic. Cardiovascular Health. What pills make you look younger? If she follows the advise it will certainly be the gift that keeps giving! Other jurisdictions do not provide guidance. It is found mostly in plant foods such as leafy greens. A daily dose of 500 to 1000 mcg of MK-4 is adequate and close to healthy ancestral consumption. I will cover food sources of Vitamin K by starting with Vitamin K1. If your goal is to achieve your Vitamin K2 MK-7 dosage target of 180 g/day using food sources you will be looking at consuming one of the following food quantities per day: Please note that I am not advocating you eat that quantity of cheese everyday. The U.S. Food and Drug Administration so far has not authorized health claims on labels for products containing Vitamin K2. Age-related compromised bioavailability of Vitamin K2. Taking a specific form of vitamin K2 seems to improve bone strength and reduce the risk of fracture in most older women with weak bones. Studies so far have shown mixed results for supplements of Vitamin K1 and Vitamin K2. Do You Need Vitamin K Supplements for Your Bone Health? How much K2 should I take daily for osteoporosis? Studies have shown that poor Vitamin K intake is linked to low bone mass, osteoporosis and fracture risk. Fat-soluble vitamin intestinal absorption: absorption sites in the intestine and interactions for absorption. .What we found was that instead of avoiding any vitamin K, which was their advice then, K2 supplementation made it unnecessary to have periodic bleeding time tests! 2015 Mar;26(3):1175-86. Cockayne S, Adamson J, Lanham-New S et al. Barbara Walther and Magali Chollet. . Researchers have since determined that Vitamin K2 reduces the calcium level in the bloodstream (thereby reducing the risk of coating the arteries) and redirects it to the skeleton for bone building (by activating the osteocalcin protein). Hi Kleanthi. Lets start with soy allergies and then discuss blood thinners (anticoagulants). Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Reproduction in whole or in part without permission is prohibited. and I take vitamin K2-m7 daily for bone health. Terms and Conditions Goncalves A, et al. Hi Georgia. Third, when we wanted to prepare an article on calcium supplements for osteoporosis, we decided to reach out to Dr. Tod Cooperman, ConsumerLabs CEO, because they had done extensive testing on the calcium supplements on the market something beyond our capabilities. I would not recommend CRL for your readers. Please consult with a dietician or nutritionist on this topic. Yoga and osteoporosis should you practice yoga if you have osteoporosis? Institute of Medicine Panel on Micronutrients. The main sources of Vitamin K2 are animal products and fermented foods. Adults should ensure they are getting between 100 and 300 micrograms of vitamin K2 per day. What is your opinion about phytic acid in foods interfering with mineral absorption? Calcium supplements: When should they be taken? - Mayo Clinic How Much Vitamin D & K2 to Take? - BetterYou However in the local pharmacy, all of the K2 supplements I can find are in the form of K2+D3. I have recently started taking a 50ug MK7 Vitamin K2 supplement.is this 50ug daily dosage supplement enough or should I start taking a 100ug daily dosage supplement? A reader on my YouTube channel shared her experience on how to make Natt more palatable. In their report, they identified two products that offered 100 g dosage of Vitamin K2/Mk-7 in isolation. Margaret is the author of three books on osteoporosis and exercise. Vitamin K is found in green leafy and cruciferous vegetables such as spinach, kale, broccoli and Brussels sprouts. First figure out how much calcium you need. We did the math to illustrate to the reader how much they would need to consume to hit the daily target of 180 micrograms of Vitamin K2. Thousands of Physical Therapists in the United States, Canada and around the world have completed her training course. I cover important topics related to osteoporosis exercise including: Enter your email address and I will start you on this free course. For example, one of our readers shared her story about working with her doctor to optimize her level of MK-7 so that did not interfere with the medication she was on for blood clotting. However, you can probably assume that you are Vitamin K2 deficient unless you are actively increasing your levels through food or supplementation. I really appreciate all the information. The good news is that you dont need much to achieve your daily Vitamin K2 target because of its concentration. I am not interested in going on osteoporosis drug therapy and have chosen to use resistance and agility training to help build bone strength and to avoid falls. However, you should be cautious about the type of Vitamin K2 you take. Vitamin K2 is more effective than Vitamin K1 for improving bone health. One site recommended taking 250 mg twice per day. Do You Need to Take Vitamin K2 with Vitamin D? - GrassrootsHealth The study showed significant competitive interactions for uptake between Vitamin D, E, A and K. It seems that the only fat soluble vitamin that did not lose out was Vitamin A when taken with vitamin E. The recommendation on Consumer Lab is that if you want to benefit from maximum absorption on your Vitamin K that you take it at least 3 hours apart from other fat soluble Vitamins (D, E and A).
